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Depo-Provera brain tumor lawsuit

If you believe you or a loved one has been diagnosed with a brain tumor linked to using Depo-Provera, you may have legal options to seek compensation. Your journey toward justice starts here.

Who may qualify for a Depo-Provera lawsuit?

Find out who may qualify for a Depo-Provera lawsuit.

How can you know if you qualify to file a Depo shot claim? You will want to speak to a Depo-Provera law firm to get the details on your specific situation. In general, you will need to:

  • Show that you or your loved one used Depo-Provera or an authorized generic version. Just two injections are enough; however, the longer you used the drug, the stronger your claim will be.
  • Have a diagnosed meningioma brain tumor after using Depo-Provera.
  • Gather medical records documenting your condition and your Depo-Provera use to establish the link.

The process of holding Pfizer liable for injuries caused by Depo-Provera is in its early stages. It is not yet known what evidence will be usable or required. A knowledgeable attorney can guide you.

Find out who may qualify for a Depo-Provera lawsuit.

How to start your Depo-Provera claim:

  1. 1

    Fill out the form to see if your case qualifies.

    Fill out the form or call us at (855) LIA-5555.

    Start by completing our online form or giving us a call to share basic details about your Depo-Provera claim.
  2. 2

    The Legal Injury Advocates team will help you with the next steps.

    Share your story with our team.

    Our team will listen to your story, answer questions and assess whether your Depo-Provera claim may qualify for legal action.
  3. 3

    Submit your medical records and history for an evaluation of your case.

    Let our legal team review your claim.

    Our experienced team, familiar with Depo-Provera lawsuit developments, will review your claim and discuss next steps.
  4. 4

    An experienced attorney will review your case and discuss the next steps if you qualify.

    Prepare for your case.

    You may need to submit medical records or important documents to help your attorney evaluate the extent of harm caused by Depo-Provera. We’ll discuss this with you.
  5. 5

    If you’re qualified, your lawsuit or litigation will begin on your journey to justice.

    Start your journey to justice.

    If your Depo-Provera claim qualifies, our legal team will guide you through the legal process to seek compensation and accountability.

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Health risks linked to Depo-Provera include bone density loss and brain tumors.

Understanding Depo-Provera and its alleged health risks

Health risks linked to Depo-Provera include bone density loss and brain tumors.

Depo-Provera is an injectable form of birth control. It is essentially an artificial hormone called progestin, similar to progesterone, which is found naturally in your body. It blocks your ovaries from releasing an egg during ovulation and stimulates your body to produce thicker mucus to help block sperm from entering your cervix.

The alleged negative health side effects are serious, even deadly. These allegations include:

A February 2024 large-scale study of 108,000 women first informed the public of the link between Depo-Provera and brain tumors.

Only after the study came out did Pfizer admit, “We are aware of this potential risk associated with long-term use of progestogens.” The company is now in the process of updating product labels and patient information leaflets with the appropriate wording. Why not warn women as far back as the product launch in 1992?

Lawsuits are being filed accusing Pfizer of knowing of the risk of tumors but not warning healthcare providers or women using the drug of this danger.

Can Depo-Provera cause brain tumors?

Can Depo-Provera cause brain tumors?

Depo-Provera is linked to the development of a kind of tumor called a meningioma. These growths are rarely cancerous, but they are still disabling, painful, and sometimes life-threatening. Dealing with this disease upsets your life and includes grueling and expensive medical care.

Warning signs of meningioma brain tumors.

Warning signs of meningioma brain tumors

You may first notice headaches, dizziness, vomiting, problems seeing or hearing, loss of smell, and in some cases, seizures and the inability to move. You may have difficulty thinking, learning, focusing, or remembering. If you have taken Depo-Provera and have any symptoms, see a doctor immediately.


Getting diagnosed with a meningioma can be scary, but not all tumors are cancerous. This kind of tumor rarely is. Still, it can grow and cause more problems over time. Depending on where your tumor is located and its size, it can be life-threatening or disabling.

Most people have the tumor removed either with open brain surgery or endoscopic surgery, which requires only a small cut and is less risky for delicate brain tissue. If the tumor is very large or can’t be removed, radiation is an option.

Companies involved in the Depo lawsuit

Companies involved in the Depo-Provera lawsuits.

Who is responsible for the health problems you suffer because you took Depo-Provera? It depends on your specific situation. You may have taken Depo-Provera, made by Pfizer, or you may have taken a generic version. None of these companies provided adequate warning to women of the danger of developing brain tumors from the drug and are accused of marketing a defective design. The companies that are currently being named in Depo shot lawsuits include:

  • Pfizer: The company that originally marketed Depo-Provera in the U.S. and did not provide a warning label about brain tumors.
  • Pharmacia & Upjohn: This company was behind the early development of the drug and was later acquired by Pfizer.
  • Viatris, Inc.: This company was formed when Mylan and Upjohn merged. They make a generic version of the drug.
  • Prasco, LLC: Another maker of a generic version of Depo-Provera.
  • Greenstone, LLC: Pfizer’s generic drug maker that markets a version of Depo-Provera.
Companies involved in the Depo-Provera lawsuits.

Important Depo-Provera lawsuit updates

Since the alleged brain tumor risks of Depo-Provera first emerged, women who suffered harm have been quickly filing lawsuits. Given the growing number of claims, they have been gathered into one court where a judge can learn the background details and not have to start from scratch with each case, duplicating the basic hearings and discovery. This group of similar cases is called a multidistrict litigation or MDL, and it speeds up the resolution of cases.

  • The Depo-Provera cases were gathered into a single MDL in the Northern District of Florida on February 7, 2025.
  • Given how recent the public awareness of the Depo-Provera and brain tumor link is, Depo-Provera lawsuits are in the early stages. No settlements have been made yet.
  • The FDA denied approval of Depo-Provera in 1967 because of elevated rates of cancer in animal studies. Between 1967 and 1978, the drug was tested on 14,000 black patients of the Grady Clinic in Atlanta, Georgia, without their knowledge or consent. The FDA denied approval of the drug again in both 1978 and 1983, before eventually granting approval in 1992.
  1. February 2024: Study links Depo-Provera to brain tumors

    Dr. Noémie Roland submitted her large-scale study demonstrating a link between Depo-Provera and brain tumors called intracranial meningiomas.

  2. November 2024: Second study released

    A Canadian study found that women who used Depo-Provera or generic versions were 3.55 times more likely to develop a meningioma.

  3. February 2025: Depo-Provera MDL formed

    Lawsuits alleging a link between Depo-Provera and generic versions to brain tumors were gathered into a single court.

Reasons to work with a lawyer for your Depo-Provera claim

Filing a Depo-Provera lawsuit is complicated and takes work. If you are suffering from a brain tumor, you and your loved ones may not have the time and energy to pursue justice.

Working with a Depo-Provera attorney who knows the ins and outs of holding pharmaceutical companies responsible and is up to date on Depo-Provera case developments can take the burden off you.

Legal Injury Advocates’ Depo-Provera lawyers will guide you through each step of the process, from gathering medical records and any other relevant documentation to filing your claim and seeking compensation for damages. You are not only taking steps to get justice for yourself, you are also helping to hold multi-billion dollar corporations responsible for their actions and products.

Why Depo-Provera victims trust Legal Injury Advocates.

Why Depo-Provera victims trust Legal Injury Advocates

Why Depo-Provera victims trust Legal Injury Advocates.

Free Initial Case Review

We’ll review your claim for free—no upfront costs, no risk.

Clear, Honest Communication

We, along with our co-counsel, will keep you informed every step of the way with straightforward, honest updates.

Legal Help Anywhere in the U.S.

Our team is ready to fight for you no matter where you live, if you qualify.

No Fee Unless You Win

You don’t pay anything unless we win your case—no risk, no obligation.

Initial Eligibility Check

Call us at (855) LIA-5555 or fill out the form to see if you qualify.

Proven Results

Our experienced legal team and co-counsel have spent decades winning cases like yours.

You may have a strong Depo-Provera claim, but time may be limited to file. Contact us to see if you qualify:

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FAQs

  • Why are women who took the Depo-Provera shot filing lawsuits against Pfizer?

    Why would you file a Depo-Provera lawsuit? People are filing lawsuits against Pfizer, the maker of the Depo-Provera shot, because they suffered serious harm to their health due to side effects and complications from it. They accuse Pfizer of:

    • Failing to disclose serious risks about the product
    • Misrepresenting the safety of the product
    • Defectively designing the drug
    • Acting negligently during research and testing

    Since it was first approved as a contraceptive by the FDA in 1992, its use has grown rapidly. The convenience of the drug led many women to decide to take the shot, up from 17 million in 1994 to 74 million in 2019. What they didn’t know was that Depo-Provera and generic versions of the drug allegedly have been linked to serious side effects, ranging from lost bone density and broken bones, blood clots and stroke, and brain tumors. Of these, studies have strongly linked brain tumors to the use of the drug.

    If you are suffering from a brain tumor related to your Depo-Provera use, do not delay in starting your Depo lawsuit. Time to file may be limited, so it is important to get started to see if your claim qualifies.

  • How did Depo-Provera get approved by the FDA?

    It took 25 years to get the FDA to approve Depo-Provera. It was rejected three times over safety concerns before legal and bureaucratic maneuvering led to the drug's approval in 1992.

  • Has Depo-Provera been recalled?

    No full recall of Depo-Provera has been issued, but several batches have been recalled over quality control issues in the past, such as contamination or incorrect labeling. You are advised to monitor FDA Depo-Provera recalls and updates.

  • Is there a Depo-Provera class action lawsuit?

    Because every Depo-Provera lawsuit is different and you may want to make individual decisions about your case and a potential settlement, you and most others will want to file in the MDL, or multidistrict litigation, instead of a class action lawsuit.

  • Has anyone received money from the Depo-Provera brain tumor lawsuit?

    Because the Depo-Provera lawsuits are just starting, no settlements have yet been made.

  • Has Pfizer been involved in Depo-Provera lawsuits before the brain tumor lawsuits?

    A Canadian class action lawsuit about bone density loss caused by Depo-Provera was settled in 2021, resulting in a $2M settlement.

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