Depo-Provera is a popular contraceptive choice, but how much do you really know about it? Discover the essentials to make an informed decision.

Depo-Provera is a widely used injectable form of birth control. While the drug may be an effective way to prevent pregnancy, do you know the potential risks involved? A recent study has linked Depo-Provera to an increased risk of developing intracranial meningioma. 

In this blog, we’ll explain what intracranial meningioma is and how Depo Provera works. Let’s get started. 

Potential Side Effects: Depo-Provera Linked to Severe Health Problems  

While Depo-Provera is effective at preventing pregnancies, it does not come without potential and dangerous side effects. Side effects can include weight gain, headaches, dizziness, and mood changes.

The drug also has more severe risks. A recent study published in 2024 by the British Medical Journal (BMJ) reports that the use of medroxyprogesterone acetate (Depo-Provera) increases the risk of intracranial meningioma. 

Additionally, Depo-Provera has also been known to increase users’ risk of osteoporosis and broken bones due to decreased bone density.  

What is Intracranial Meningioma

Intracranial meningioma, which has been linked to Depo-Provera use, is a tumor that forms in the tissue layers that cover the brain and spinal cord. These tumors are usually benign but can be cancerous. 

Even some benign intracranial meningiomas can become life-threatening if they press on nearby nerves or other areas of the brain. 

Meningiomas are usually slow-growing tumors and may not present noticeable symptoms in patients until they grow quite large. The symptoms also depend on the area of the brain being affected by the tumor.

Here are some neurologic symptoms that can be present depending on the location of the tumor: 

  • Loss of smell 
  • Lower body paralysis 
  • Eye bulging 

Additionally, these tumors can cause other symptoms, such as headaches, hearing loss, dizziness, vomiting/nausea, seizures, memory problems, and vision changes. 

If you think you may have intracranial meningiomas, contact your doctor immediately. 

Understanding Depo-Provera: What is it? 

Depo-Provera is a name-brand drug for medroxyprogesterone acetate, which is a hormone progestin contraceptive injection. Typically, the shot is given once every three months. 

The birth control method is known for its convenience and effectiveness. It is a popular choice for those seeking a long-term, low-maintenance contraceptive solution.

How Depo-Provera Works

Depo-Provera works by releasing medroxyprogesterone acetate into the recipient’s bloodstream. This hormone works to prevent pregnancy in a few ways. 

It prevents ovulation, meaning that no egg is released for fertilization. Additionally, it thickens the cervical mucus, making it difficult for sperm to enter the uterus. It also thins the uterus lining, reducing the likelihood of implantation.

The science behind Depo Provera’s effectiveness lies in its ability to maintain consistent hormone levels over an extended period. This sustained hormone presence ensures continuous contraceptive protection.

Why People Use Depo-Provera

Depo-Provera is the favored birth control choice for 74 million users, according to the BMJ study. Users appreciate its convenience; a single injection provides three months of protection, eliminating the need for daily pills or frequent interventions.

This method of birth control can also stop menstruation, which can be an appealing side effect for some users. 

Furthermore, Depo-Provera can be particularly beneficial for individuals who cannot use estrogen-based contraceptives due to medical reasons. 

Deciding which contraceptive method is right for you involves weighing its benefits against its potential drawbacks. Consider your lifestyle, medical history, and personal preferences.

Consulting with a healthcare professional can provide personalized insights and help you make an informed decision. They can address any concerns and assist you in exploring alternative contraceptive options if needed. 

Depo-Provera Law Suits

The discoveries from the BMJ study have led to lawsuits against the manufacturers of Depo-Provera. The lawsuits are against Depo-Provera’s manufacturer, Pfizer, and claim that users weren’t warned about the risk of intracranial meningiomas.  

These lawsuits are still in their infancy as more information unfolds. 

In addition to these lawsuits, other claims have been filed in the past against the drug due to its link to bone density loss. 

Read More Blogs Here